The foundation has focused its initial efforts on developing a working pathogenesis (and a cure) for one of the most chronic autoimmune diseases, Sarcoidosis.

Sarcoidosis is an often-fatal Th1 inflammatory disease which can damage the lungs, heart, eyes, brain, liver, kidneys and soul. More than a century after its discovery, sarcoidosis patients are still being told it has no known cause and no known cure.

Ongoing research includes a Internet-based, phase II clinical trial of a succesful antibiotic therapy for sarcoidosis (at SarcInfo.com). Currently the study is supporting a cohort of nearly 200 sarcoidosis patients. Two papers have already been published describing the preliminary results:

	Marshall TG, Marshall FE: Antibiotics in Sarcoidosis - Reflections on the First Year. JOIMR 2003;1(3):2
	Mangin M: Observations of Jarisch-Herxheimer Reaction in Sarcoidosis Patients. JOIMR 2004;2(1):1

Rheumatoid Arthritis, Lupus and Parkinson's

During 2004, the foundation has also begun to informally trial a similar protocol in a small number of Rheumatoid Arthritis and Lupus patients. Foundation directors have published a paper describing why these diseases, in conjunction with Parkinson's disease, have very similar genetics and biochemistry to Sarcoidosis:

Marshall TG, Marshall FE: Sarcoidosis succumbs to antibiotics - implications for autoimmune disease. Autoimmunity Reviews, "in press", doi:10.1016/j.autrev.2003.10.001

But the most important task for the foundation is outreach, to ensure that the training of new medical graduates includes an understanding of the special type of antibiotic resistant bacteria which seem to be causing so many of the 'autoimmune' diseases. Research scientists may already understand the cause of 'autoimmune' disease, but only a fundamental change in clinical medicine, a change in the way we train young physicians, will bring the benefit of that knowledge to the population as a whole.

The foundation is actively negotiating with the National Institutes of Health on two fronts: firstly, campaigning for more widespread clinical studies, and secondly by applying a critical eye to NIH publications - ensuring that they represent the most up-to-date science available.

We need your help. The volunteers who staff this foundation can publish papers, and donate their time to studies, but ultimately the outreach task can only be tackled when adequate funding is available. The foundation intends to present papers at international conferences during 2004. We also need to send recovered patients, those who really understand how to beat these diseases, to the major medical conferences.

With your help the foundation will spread the knowledge of how to beat these diseases, and ensure that our children, and our childrens' children, do not have to suffer and die from the diseases still being considered 'autoimmune.'

Patient Outreach Sponsored by the Foundation:-

	Moderated Discussion of The Marshall Protocol in CFS, RA, chronicLyme, and Autoimmune Disease
	Up-to-date Sarcoidosis Answers for Physicians, Nurses and Patients

On June 30, 2004, an interview with Dr Trevor Marshall was published at ImmuneSupport.com.